Search results for " Synbiotics"

showing 3 items of 3 documents

Gut microbiota and aging-A focus on centenarians.

2020

Gut microbiota (GM) is a dynamic organ throughout the lifespan. Aging is a complex process that comprises a plethora of mechanisms such as senescence, immunosenescence and inflammaging, representing important pathways of age-related diseases. GM structure could both influence and be influenced by aging occurring changes within the host. A unique category of long living individuals exists, namely centenarians that have the outstanding capacity to adapt to various challenges. Longevity seems to be associated with certain GM which, among other factors, might render individuals more resistant to age-related diseases and subsequently to long living. Diet, prebiotics, probiotics and synbiotics ma…

0301 basic medicineSenescenceAgingSynbioticsmedia_common.quotation_subjectLongevitySynbioticsGut microbiotaBiologyGut flora03 medical and health sciences0302 clinical medicineCentenariansHumansAging Centenarians Gut microbiota Prebiotics Probiotics Synbiotics Aged 80 and over Aging Gastrointestinal Microbiome Humans Longevity Prebiotics Probiotics SynbioticsMolecular Biologymedia_commonAged 80 and overProbioticsLongevityImmunosenescencebiology.organism_classificationGastrointestinal Microbiome030104 developmental biologyPrebioticsImmunologyMolecular Medicine030217 neurology & neurosurgery
researchProduct

Administration of a Synbiotic to Free-Living Elderly and Evaluation of Serum Cytokines. A Pilot Study

2010

Ten free-living elderly were administered with a synbiotic [fermented milk containing Lactobacillus rhamnosus Gorbach and Goldin (LGG)] and oligofructose as a prebiotic for one month. Serum cytokines were evaluated before (T(0)) and after (T(1)) synbiotic administration. At T(0), values of Interleukin (IL)-12, IL-6, IL-10, IL-1beta and Tumor Necrosis Factor (TNF)-alpha were lower than normal controls, with the exception of IL-8, thus confirming previous results on the impairment of both innate and adaptive responses in elderly. At T(1), the synbiotic was able to significantly increase, depressed values of IL-1, IL-6 and IL-8 with a trend to a modest increase for the restant cytokines. In co…

Cytokines immunosenescence Lactobacillus rhamnosus Gorbach and Goldin (LGG) oligofructose probiotics synbiotics elderly.medicine.medical_specialtySynbioticsmedicine.medical_treatmentPilot ProjectsGastroenterologyImmune systemLactobacillus rhamnosusInternal medicineDrug DiscoverymedicineHumansAgedAged 80 and overPharmacologybiologyLacticaseibacillus rhamnosusbusiness.industryProbioticsInterleukinImmunosenescenceFlow Cytometrybiology.organism_classificationInterleukin 10CytokineImmune SystemImmunologyInterleukin 12Cytokinesbusiness
researchProduct

Probiotics, prebiotics and symbiotics in inflammatory bowel diseases: state-of-the-art and new insights

2013

Inflammatory bowel disease (IBD) consists of two distinct clinical forms, ulcerative colitis (UC) and Crohn's disease (CD), with unknown aetiology, which nevertheless are considered to share almost identical pathophysiological backgrounds. Up to date, a full coherent mechanistic explanation for IBD is still lacking, but people start to realize that the pathogenesis of IBD involves four fundamental components: the environment, gut microbiota, the immune system and the genome. As a consequence, IBD development might be due to an altered immune response and a disrupted mechanism of host tolerance to the non-pathogenic resident microbiota, leading to an elevated inflammatory response. Consideri…

Settore BIO/17 - IstologiaPrebioticsMicrobiotaProbioticsHumansProbiotics Prebiotics Synbiotics Inflammatory Bowel DiseaseInflammatory Bowel Diseases
researchProduct